Endplate discogenic signal changes at the T11-12 vertebral level refer to alterations in the bone marrow and endplate of the intervertebral disc, typically seen on MRI scans. These changes often indicate degeneration or pathology related to the disc, such as disc herniation or osteoarthritis, and may correlate with Back pain or other neurological symptoms. The signal alterations reflect changes in the hydration and composition of the disc and adjacent vertebrae, which can impact the overall health of the spinal column.