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When a protein is phosphorylated it can act on multiple down stream target. So if 1 molecule, lets say Calcium, can lead to phosphorylation of 1 other molecule which can act on 10 molecule. In this case you get a 10x amplification. This is necessary sometimes because certain states, such as, calcium mobilization is very short acting and goes a way very quickly.

Another way to look at it is that a single person can tell another person something; this person can now go and tell 10-20 other people. Also the first person fatigues easier while the 2nd does not, so that the message can get past on longer.

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How is phosphorylation important in a signal transduction cascade?

Phosphorylation plays a critical role in signal transduction cascades by regulating protein activity. It can activate or inactivate proteins, leading to changes in cellular pathways and ultimately altering cellular responses to external signals. Phosphorylation serves as a key mechanism for transmitting signals from the cell surface to the nucleus to elicit a specific cellular response.


What physical event represents the receipt of an intercellular signal?

The binding of a signaling molecule, such as a hormone or neurotransmitter, to its respective receptor on the cell membrane represents the receipt of an intercellular signal. This binding triggers a cascade of events inside the cell, leading to a cellular response.


What does a signal transmitted via phosphorylation of a series of proteins do?

Phosphorylation of proteins in a signaling cascade amplifies and propagates the signal within the cell. It can lead to activation or inactivation of cellular processes, such as gene expression, cell growth, differentiation, or cell death. Ultimately, phosphorylation serves as a crucial mechanism for cells to respond to external stimuli and maintain cellular homeostasis.


Describe how signal amplification is accomplished in target cells?

Signal amplification in target cells can be achieved through the activation of downstream signaling cascades, leading to the phosphorylation and activation of multiple intermediate proteins. These activated proteins can further amplify the signal through enzymatic reactions, resulting in a robust cellular response. Additionally, some signaling pathways can involve feedback loops that enhance signal transduction and amplify the initial signal.


How is phosphorylation important in a transduction cascade?

Phosphorylation will turn an inactive protein into an active one, which triggers another response in the cell.


Why amplifier is required?

Amplifiers are the device which are used to amplify a signal Multistage amplifier are use to amplify a signal into a desire level


What is the verb for amplify?

Amplify is a verb. This device amplifies the signal from the microphone so that it can be heard.


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