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When a protein is phosphorylated it can act on multiple down stream target. So if 1 molecule, lets say Calcium, can lead to phosphorylation of 1 other molecule which can act on 10 molecule. In this case you get a 10x amplification. This is necessary sometimes because certain states, such as, calcium mobilization is very short acting and goes a way very quickly.

Another way to look at it is that a single person can tell another person something; this person can now go and tell 10-20 other people. Also the first person fatigues easier while the 2nd does not, so that the message can get past on longer.

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How is phosphorylation important in a signal transduction cascade?

Phosphorylation plays a critical role in signal transduction cascades by regulating protein activity. It can activate or inactivate proteins, leading to changes in cellular pathways and ultimately altering cellular responses to external signals. Phosphorylation serves as a key mechanism for transmitting signals from the cell surface to the nucleus to elicit a specific cellular response.


What is meant by a signal cascade?

A signal cascade, also known as a signaling cascade, refers to a series of biochemical events in which a signal or stimulus triggers a sequence of reactions within a cell. This process typically involves the activation of proteins and enzymes through phosphorylation or other modifications, leading to a specific cellular response. Signal cascades are essential for various cellular functions, including growth, differentiation, and response to environmental changes. They amplify the initial signal, allowing for a robust response to external stimuli.


What physical event represents the receipt of an intercellular signal?

The binding of a signaling molecule, such as a hormone or neurotransmitter, to its respective receptor on the cell membrane represents the receipt of an intercellular signal. This binding triggers a cascade of events inside the cell, leading to a cellular response.


What does a signal transmitted via phosphorylation of a series of proteins do?

Phosphorylation of proteins in a signaling cascade amplifies and propagates the signal within the cell. It can lead to activation or inactivation of cellular processes, such as gene expression, cell growth, differentiation, or cell death. Ultimately, phosphorylation serves as a crucial mechanism for cells to respond to external stimuli and maintain cellular homeostasis.


How is phosphorylation important in a transduction cascade?

Phosphorylation will turn an inactive protein into an active one, which triggers another response in the cell.


Describe how signal amplification is accomplished in target cells?

Signal amplification in target cells can be achieved through the activation of downstream signaling cascades, leading to the phosphorylation and activation of multiple intermediate proteins. These activated proteins can further amplify the signal through enzymatic reactions, resulting in a robust cellular response. Additionally, some signaling pathways can involve feedback loops that enhance signal transduction and amplify the initial signal.


Why amplifier is required?

Amplifiers are the device which are used to amplify a signal Multistage amplifier are use to amplify a signal into a desire level


What amplifies communication from a signal molecule?

Receptor proteins on the cell membrane or inside the cell amplify the signal from a signal molecule by initiating a cascade of intracellular events, leading to a cellular response. This amplification allows the cell to respond effectively to low concentrations of the signal molecule.


Why is the cascaded range called the cascade certain?

The term "cascade" refers to the process of connecting multiple ranges in series, where the output range of one stage becomes the input range of the next stage in a cascading fashion. This technique helps improve overall signal handling and dynamic range by distributing the gain across multiple stages instead of relying on a single stage to amplify the signal.


What is the verb for amplify?

Amplify is a verb. This device amplifies the signal from the microphone so that it can be heard.


What are advantages and disadvantages of multistage amplifier?

to amplify a small signal to sufficient level,so that it can travel to a large distance from first stage till the last stage


What would be an example of a protein receptor initiating a signal transduction cascade?

An example of a protein receptor initiating a signal transduction cascade is the insulin receptor. When insulin binds to its receptor on the cell membrane, it activates the receptor’s intrinsic kinase activity, leading to autophosphorylation. This event triggers a cascade involving the phosphorylation of downstream signaling proteins, such as IRS (Insulin Receptor Substrate), which then activates pathways like the PI3K/Akt pathway that regulate glucose uptake and metabolism. This signaling ultimately leads to physiological responses, including increased glucose transport into the cell.