Not unless you are talking about something that "belongs" to the acronym. To make a word plural, just add s, or in some cases drop the y and add es. But to make acronym plural, just add s.
Either can be correct depending on the acronym.
spqr
Using Octopus's garden is correct if the Octopus here refer to a name and not to octopus, a mollusk.
The C in the acronym RACE stands for: Contain or Confine the fire
W S E is an acronym. This set of letters can stand for many different things. The most common meaning of these letters is west south east.
Either can be correct depending on the acronym.
"Science" is not an acronym.
HIPAA
Yes, LASIK is the correct acronym for laser-assisted in situ keratomileusis.
Laser is an acronym for Light Amplification by Stimulated Emission of Radiation.
The correct spelling is "radar." (acronym from RAdio Detection And Ranging)
spqr
I think you are using the wrong word.
Using Octopus's garden is correct if the Octopus here refer to a name and not to octopus, a mollusk.
Acronym
s share your time
Science is not an acronym