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It means move - you are blocking the path in a literal sense. It can also mean that you are or you represent any kind of obstacle to my progress, physical or otherwise, and I want you to stop hindering me. Both of these meanings have a confrontational tone to them, depending on the specific use.

The expression can also be used in a more lighthearted way. Say that I am just opening a business, and I am very enthused about the possibility that the business will really take off (succeed quickly and dramatically). I might say something like: "Once my doors open for business, get outta my way! I'm gonna give the competition a run for their money!" (I'm going to give them some competition that they will have to deal with.)

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15y ago

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