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'little' is used to mean 'none' or 'no' eg: Obama's presidency had little impact in countering the economic crisis in the USA, which continued to worsen for a much longer duration. 'a little' is used to mean 'some' or 'small amount of' eg: Obama's presidency had a little impact in countering the economic crisis in the USA, eventually resulting in a better financial situation for the Americans.

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Q: What is the quantitative difference between 'Little' and 'A Little'?
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