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The engine harness on a Mercedes E280 is typically located near the engine, connecting various sensors, actuators, and components to the engine control unit (ECU). It runs along the engine block and may be routed through the engine bay to provide connections to the ignition system, fuel injectors, and other critical systems. Accessing the harness may require removing certain engine covers or components, depending on the specific model year. Always refer to the vehicle’s service manual for precise locations and instructions.

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