Osteosarcoma is a cancerous (malignant) bone tumor that usually develops during the period of rapid growth that occurs in adolescence, as a teenager matures into an adult.
Alternative NamesOsteogenic sarcoma
Causes, incidence, and risk factorsOsteosarcoma is the most common cancerous (malignant) bone tumor in youth. The average age at diagnosis is 15. Boys and girls have a similar incidenceof this tumor until late adolescence, at which time boys are more commonly affected.
The cause is not known. In some cases, osteosarcoma runs in families, and at least one gene has been linked to increased risk. This gene is also associated with familial retinoblastoma, a cancer of the eye that occurs in children.
Osteosarcoma tends to occur in the bones of the:
This cancer occurs most commonly in larger bones and in the area of bone with the fastest growth rate. Osteosarcoma can occur in any bone, however.
Although it is rare, osteosarcoma can occur in adults.
SymptomsTreatment usually starts after a biopsy of the tumor.
Before major surgery to remove the tumor, chemotherapy is usually given. Chemotherapy is also used to kill or shrink any cancer cells that may have spread to other parts of the body.
Common chemotherapy medicines include:
Surgery is used after chemotherapy to remove any remaining tumor. In most cases, surgery can remove the tumor while saving the affected limb (this is called limb-salvage surgery). Rarely, more radical surgery (such as amputation) may be necessary.
Support GroupsAssociation of Cancer Online Resources -- www.acor.org
Cure Search (formerly the National Childhood Cancer Foundation) --www.curesearch.org
Expectations (prognosis)If the tumor has not spread to the lungs (pulmonary metastasis), long-term survival rates are very high. If the cancer has spread to other parts of the body, there is still a good chance of cure with effective treatment.
ComplicationsCall your health care provider if you have persistent bone pain, tenderness, or swelling.
ReferencesSkubitz KM, D'Adamo D. Sarcoma. Mayo Clin Proc. 2007;82:1409-1432.
Baker MH. Bone tumors: primary and metastatic bone lesions. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 212.
osteosarcoma
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Osteosarcoma is a bone cancer. -I have this type of cancer. if you would like more information, go to google, a search "Osteogenic Sarcoma."
Osteo means bone and sarcoma means tumour, so the term osteosarcoma means a malignant bone tumour
Alkaline phosphatase is a biomarker that is often elevated in individuals with osteosarcoma, a type of bone cancer. Monitoring alkaline phosphatase levels can help clinicians assess disease progression, response to treatment, and detect potential metastasis of osteosarcoma. Elevated levels of alkaline phosphatase may indicate an aggressive form of osteosarcoma and can be used to guide treatment decisions.
Buddy had osteosarcoma.
A malignant tumor of bone in which there is a proliferation of osteoblasts.
The death rate of osteosarcoma per year is estimated to be around 1-2 per million people globally. However, survival rates for osteosarcoma have significantly improved in recent years due to advancements in treatment strategies such as surgery, chemotherapy, and targeted therapies.
Osteosarcoma is a type of bone cancer that arises from abnormal growth of osteoblasts, which are the cells that form new bone tissue. This leads to the formation of immature bone tissue (osteoid) within the tumor. Osteosarcoma commonly occurs in the long bones of the body, such as the arms and legs, and can metastasize to other organs, particularly the lungs.
He was diagnosed with osteosarcoma, cancer of the knee,
Skeletal and muscular systems
osteosarcoma