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That depends on which part of the sentence the phrase is in (whether those people are the subject of the sentence, or the object of it). If you're the subject of the sentence, it's "I" ("Your best friend and I want to take you to the club"); if you're the object, it's "me" ("Please do this for your best friend and me"). In either case, you can take the best friend out of the sentence for a moment, to determine whether you are "I" or "me".

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15y ago

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