What relation are you to your mother's sister's grandson?

Answer 1

If your wife's nephew is not a son of one of your siblings, there is no relationship between your mom and either your wife's nephew or his son.

If your wife's nephew is the son of one of your siblings, then he is your mother's grandchild.

Answer 2

Your mother's nephew is your first cousin. His daughter's son is his grandson and your first cousin, twice removed.

Answer 3

Your mother's sister is your aunt. Your aunt's grandson is your First Cousin, once removed.

Answer 4

Your mother's niece is your first cousin. The son of your first cousin is your first cousin, once removed.