Your great uncle's son's son is his grandson. Your great uncle is the brother of one of your grandparents.
Children of siblings are first cousins to each other.
Grandchildren of siblings are second cousins to each other.
Great grand children of siblings are third cousins to each other.
So you and your great uncle's grandson are second cousins to each other.
your cousin
Your niece's son's son is her grandson. He is your great great nephew and you are his great great aunt or great great uncle, depending on your gender.
Your sister's son is your nephew His sons are your grandnephews, and his daughters are your grandnieces.
It means you have (or had) at least two uncles and at least two great-uncles, and that is all it means.
great uncle
Your son's children are your grandchildren.
His great uncle
Your sister's son is your nephew His sons are your grandnephews, and his daughters are your grandnieces.
Your grandfather's son's son could be:you (if you are a boy)your brotheryour first cousin
They share a common Grandparent. That makes them first cousins.
Your nephew's son is your great nephew.
Great aunty