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What is the enzyme that connects the okasaki fragments and participates in DNA repair?
The enzyme that connects Okazaki fragments during DNA replication is DNA ligase. DNA ligase is also involved in repairing nicks in the sugar-phosphate backbone of DNA during processes such as base excision repair and mismatch repair.
What DNA replication enzyme attaches okazaki fragments as a continuous strand of DNA?
Ligase joins okazaki fragments to each other to form a continuous strand of DNA
Name the enzyme joining Okazaki fragments?
DNA ligase is the enzyme that is responsible for joining Okazaki fragments on the lagging strand during DNA replication. It catalyzes the formation of phosphodiester bonds between the fragments, sealing the gaps in the newly synthesized DNA.
In the replication of DNA what is the name of the enzyme which joins the lagging strands together?
The enzyme responsible for joining the Okazaki fragments on the lagging strand during DNA replication is DNA ligase. DNA ligase helps to seal the nicks between the newly synthesized Okazaki fragments, creating a continuous strand of DNA.
Okazaki fragments are joined together by?
During DNA replication Okazaki fragments are joined together by DNA polymerase. Remember that Okazaki fragments start with an RNA primer so RNAse H is need to remove the primer follwed by DNA plymerase to add nucleotides and finally DNA ligase to seal the single strand nick.
What enzyme used to join the DNA strand that is replicated in small segments called?
DNA ligase is the enzyme used to join the DNA strand that is replicated in small segments called Okazaki fragments. It helps to seal the breaks in the sugar-phosphate backbone of the DNA, ensuring that the fragments are connected into a continuous strand.
Which enzyme joins the okazagi fragments together on the lagging stand during DNA replication?
DNA ligase joins the Okazaki fragments together on the lagging strand during DNA replication. It catalyzes the formation of phosphodiester bonds between the fragments to create a continuous strand.
Why is DNAligase popularly called the molecular glue?
DNA ligase is called the molecular glue because it catalyzes the formation of a phosphodiester bond between adjacent DNA fragments, effectively "gluing" them together. This enzyme plays a crucial role in DNA replication, repair, and recombination by joining the Okazaki fragments on the lagging strand and sealing nicks in the DNA backbone.
What is lagging strand in replication of DNA?
The two strands of DNA in animal cells are arranged backwards to each other - the start of one is paired with the ending of the other. However, the enzyme that replicates DNA (DNA polymerase) can only work from start to finish. On one strand, DNA polymerase can work front to back in a continuous chain - the strand that allows this is called the leading strand because it "leads" in completion status. On the other strand, the DNA polymerase has to work backwards in pieces and then put the pieces back together into a single chain - the strand that causes this is called the lagging strand because it "lags behind" the other in completion status.
What enzyme binds fragments of DNA on the lagging strand?
DNA ligase is the enzyme that binds together the Okazaki fragments on the lagging strand during DNA replication. It forms phosphodiester bonds between adjacent nucleotides to create a continuous strand of DNA.
What is the function of DNA ligase in DNA replication?
it ties the chunks of dna together
What okazaki fragments are?
In DNA replication, the two DNA strands acting as templates need to be synthesized simultaneously. DNA polymerase is an enzyme which can synthesize the DNA only in 5' to 3' direction.the two template strands are anti-parallel to each other and their complementary strands are synthesized in different direction. In one of the strand DNA is synthesized continuously by adding nucleotides at 3'-OH end. this is referred as 'leading strand' synthesis. the other strand to be synthesized is replicated in short fragments referred 'Okazaki fragments' named after their discoverer Reiji Okazaki.
