What is one irony in my sister's keeper?

Answer 1

Situational Irony.

Answer 2

One irony in "My Sister's Keeper" is that Anna fights for medical emancipation from her parents, who have always supported her sister's medical needs, despite the fact that her sister challenges the family's unity when she decides she no longer wants Anna's help. This highlights the complex dynamics of family relationships and the sacrifices made in the name of love and responsibility.