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I have not had good experiences when I have tried and I am only on 100mg for migraines. It definitely intensifies the effect of the Topamax and i feel completely out of it the next day and I have never been one to be hung over. If I were you I would maybe have one drink and pass on the rest, trust me it is not worth it.

Blacked out a majority of the time on minimal drinks. Do not mix!

has anyone tried taking Nyquel or sinus meds on Topamax did they have bad side affects?

What else can I help you with?