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What causes Lesch-Nyhan syndrome?

GaleEncyofNeuroDis ∙

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∙ 14y ago

Updated: 11/9/2022

The syndrome is caused by a severe change (mutation) in the HPRT gene . Since the HPRT gene is located on the X chromosome, Lesch-Nyhan syndrome is considered an X-linked disorder and therefore only affects males.

Wiki User

∙ 14y ago

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