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Human Leukocytes Antigen

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What does HLA stand for in HLA gene family?

HLA in the HLA gene family stands for Human Leukocyte Antigen. The genes are responsible for producing antigens in the body to fight viruses and bacteria.


What has the author Jan Klein written?

Jan Klein has written: 'Natural history of the major histocompatibility complex' -- subject(s): Major histocompatibility complex, HLA histocompatibility antigens, Histocompatibility 'Immunology' -- subject(s): Allergy and Immunology, Immune system, Immunity, Immunology, Physiology 'Neuroimaging'


What are HLA haplotypes?

HLA haplotypes are specific combinations of alleles at the human leukocyte antigen (HLA) gene loci, which are crucial for the immune system's function in recognizing foreign molecules. Each individual inherits one haplotype from each parent, resulting in a unique pair that influences compatibility for organ transplants and susceptibility to certain diseases. These haplotypes play a significant role in autoimmune conditions and the body's response to infections. Understanding HLA haplotypes is essential in fields like transplantation medicine and immunology.


How many classes are there of HLA gene products?

There are three classes of HLA gene products: Class I (HLA-A, HLA-B, HLA-C), Class II (HLA-DP, HLA-DQ, HLA-DR), and Class III (complement proteins). These gene products play a crucial role in the immune system by presenting antigens to T cells and regulating immune responses.


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