answersLogoWhite

0

An LE prep (lupus erythematosus preparation) is when blood is taken out of the patient and left shaking and letting stand non-clotted blood. Damaged cells will release their nuclei, which get coated with anti-nuclear antibodies (if present, as in the case of lupus) and a blue dye is put in so that the clumbed nuclei are stained blue. These clumbs are subsequently phagocytosed by Fc-bearing intact monocytes and neutrophils, which produces blue-stained monocytes and neutrophils (the LE cells). The test is positive in 70-90% of SLE patients.

User Avatar

Wiki User

∙ 15y ago

What else can I help you with?

Related Questions