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I believe it was Louis Pasteur while he was working on finding the cause for the failing French wine industry. While others had observed yeast cells in the microscope before him, winemaking was at the time believed to be a purely chemical process and the microbes present were inconsequential. Pasteur (a chemist hired to solve this "chemical" problem) showed that the yeast cells fermented the juice making wine, but bacterial contaminates fermented the alcohol to lactic acid ruining the wine (showing the problem was really biological, not "chemical" as previously believed).

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In an experiment a scientist makes a radioactively labeled probe using yeast DNA she then discovers that the probe hybridizes to a small segment?

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