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The Mulliken-Barker reaction is a chemical process that involves the reaction of an aryl or alkyl halide with a nucleophile in the presence of a palladium catalyst, typically in a cross-coupling reaction. This reaction facilitates the formation of carbon-carbon bonds, allowing for the synthesis of complex organic molecules. It is particularly useful in the field of organic synthesis and medicinal chemistry for constructing diverse chemical libraries. The reaction highlights the utility of palladium catalysis in facilitating transformations that are otherwise challenging.

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Why is mullikan barker test done in basic medium?

The Mullikan-Barker test is performed in a basic medium to ensure optimal conditions for the reaction between the analyte and the reagents used in the test. In basic conditions, certain reactions, such as the formation of colored complexes, are enhanced, allowing for improved sensitivity and specificity in detecting the presence of specific substances. Additionally, a basic environment can help prevent the degradation of sensitive compounds that might occur in acidic conditions.


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