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In which area of the body would you expect to find most of merkel disks and meissner's corpuscles?
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The Merkel's disks are the receptors for pressure.
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Sensory receptors in the dermis include: free nerve endings, pacinian corpuscles, and hair follicle receptors The mechanoreceptors of the skin are the meissner's corpuscles (which respond to light touch), the pacinian corpuscles (deeper in the dermis and respond to pressure), and the merkel's disks (closely related to the merkel's cells located in the epidermis and respond to light touch). The nociceptors are pain receptors that recognize hot, cold, and pain.
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Sensory receptors in the skin (cutaneous receptors) are generally of the mechanoreceptor, nociceptor, and thermoreceptor types. Mechanoreceptors sense pressure (such as touch) and vibrations and for example include Meissner corpuscles, Merkel disks, Ruffini corpuscles and Pacinian corpuscles. Nociceptors sense pain caused by damage. Thermoreceptors convey feelings of heat or cold. Chemoreceptors that sense the presence of specific chemicals are sometimes present depending on location but are generally not found on exposed skin.
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The DCML- Dorsal column mediated leminiscal - system is one of the central pathways of the somatosensory system. This system is involved in mediating fine and discriminating touch. A-beta fibrers such as the Meisnerr's corpuscles, Merkel disks, Ruffinni corpuscles and Pacinian corpuscles are involved in this pathway. They are called Tactile fibres. Axons from tactile afferents ascends spinal cord and synapse on the 2nd order of the Dorsal column nuclei of the medulla. Axons of the 2nd order neurons cross to other side of brainstem and ascend to the VP (ventral posterior) complex of thalamic nuclei. The 3rd order of the thalamic nuclei project onto the primary somatosensory cortex of the mammalian brain where the information is processed. The cerebral cortex consists of 2 types of neurons- the pyramidal neurons which is excitatory; and stellate neurons which are excitatory and inhibitory. The 3rd neuron has its cell body still in the VP of the thalamic nuclei and ends in the parietal lobe- the postcentral gyrus.
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