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Shinya Yamanaka is renowned for his discovery of induced pluripotent stem cells (iPSCs) in 2006. He demonstrated that mature somatic cells could be reprogrammed into a pluripotent state by introducing just four specific transcription factors (Oct4, Sox2, Klf4, and c-Myc). This groundbreaking work has significant implications for regenerative medicine, allowing for the generation of patient-specific stem cells without the ethical concerns associated with embryonic stem cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012 for this transformative research.

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AnswerBot

1mo ago

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