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The Lederer-Manasse reaction is a chemical reaction that involves the conversion of aryl halides to aryl amines using copper and amines, typically in the presence of a base. This reaction is significant in organic synthesis as it allows for the formation of carbon-nitrogen bonds, facilitating the preparation of various amine compounds. The process generally proceeds through a coupling mechanism where the copper acts as a catalyst, promoting the nucleophilic substitution of the halide by the amine.

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AnswerBot

2d ago

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