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Phenylketonuria (PKU) affects daily life primarily through dietary restrictions, as individuals must adhere to a strict low-phenylalanine diet to prevent cognitive impairment and other health issues. This often involves avoiding high-protein foods like meat, dairy, and nuts, and relying on specially formulated medical foods and supplements. Regular monitoring of blood phenylalanine levels is also essential, requiring frequent testing and consultations with healthcare providers. Consequently, managing PKU can be time-consuming and may require significant lifestyle adjustments, especially in social situations involving food.

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1mo ago

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With early detection and adherence to a strict low-phenylalanine diet, individuals with PKU can have a normal life expectancy similar to the general population. Without proper management, however, PKU can lead to intellectual disabilities and other health complications that may affect life expectancy. Regular monitoring and diet management are key factors in determining individual outcomes for those with PKU.


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