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If done slowly, quite well. Venous gas pressure is sub-atmospheric so that excess gasses can be removed, arterial blood gas pressure is at ambient pressure and is excellent at distributing any increase in pressure.

However ... there are limits. Drop to fast and you get ear aches or even the bends,

(and low enough and you get hypoxia or boiling blood).

Too high and the toxic properties of oxygen become apparent AND the anesthetic properties on nitrogen starts ("rapture of the deep").

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