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The number of cells in an organism constantly changes. Cells die and are replaced by new cells all the time. As I type, cells on my fingertips die, fall off and new cells replace them. There are far too many cells to count in any organism, and they are constantly changing. Here's an interesting fact- if one of the cells on the tip of your nose was the size of a football pitch, your head would be the same size (roughly) as the world!

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