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The Darwins had ten children: two died in infancy, and Annie's death at the age of ten had a devastating effect on her parents. Charles was a devoted father and uncommonly attentive to his children. Whenever they fell ill he feared that they might have inherited weaknesses from inbreeding due to the close family ties he shared with his wife and cousin, Emma Wedgwood. He examined this topic in his writings, contrasting it with the advantages of crossing amongst many organism Despite his fears, most of the surviving children went on to have distinguished careers as notable members of the prominent Darwin-Wedgwood family. Of his surviving children, George, Francis and Horace became Fellows of the Royal Society, distinguished as astronomer, botanist and civil engineer, respectively. His son Leonard, on the other hand, went on to be a soldier, politician, economist, eugenicist and mentor of the statistician and evolutionary biologist Ronald Fisher. ---- Quoted from wikipedia

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