What can be the possible method of performing meta-analysis on the single arm type of studies?

Answer 1

Hi everyone, I have collected the research data for the meta-analysis. It includes the sample size, mean and the standard deviation of each study. I need to perform the single arm-studies observation on the data which means it can contain only one group; either control or intervention.

So, can you suggest to me a software that is suitable for the meta-analysis of these studies?

I would also like to ask about what needs to be done with the missing data because I believe it can not be ignored without giving a rational reason.

Answer 2

Hello, because you have mean, sample size and SD in your data set, you should perform a meta-analysis where the mean can be considered as the effect size measure. I got this information from the service provider FiveVidya who assisted me in meta-analysis.

Also, remember to manually put the sample size as one of the options while setting commands in your meta-analysis. This will come in handy when you need to adjust the individual study weights during the analysis.

Stata is a commonly used software for meta-analysis. You can use the “study size” option to set the “meta set command”. Before performing the analysis, make sure that the SD has been converted to SE for that. There is a formula given in Cochrane’s handbook if you’d like to search, otherwise you can also connect with the team of Chanakya Research for more software opinions as they can suggest you your research related advice and might tell you a better option.

Good luck with your research.