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"Very big" depends on what scale one uses. In anatomical terms, "gross" objects are comparatively large things able to be seen with the naked eye. Similarily, things that are "macroscopic" are visible without microscopes or magnification. Many times, scientists use prefixes to denote size, where mega, giga, and tera (1 million, 1 billion, and 1 trillion, respectively) are the most common to describe very large masses or quantities. For example, a gigabyte is typically equal to 1 billion bytes. Scientists often use specific terms or units for large objects or to compare sizes instead of adjectives to describe them--supergiants are enormous stars, newtons are units of force (higher value, larger force), etc. Thus, there aren't many general terms that mean "very big" in scientific jargon--each area of science has its own values and words that relate to certain events or objects. However, if you simply want sophisticated "big" words (pun intended), try using stratospheric, cyclopean, behemoth, or leviathan. Sources like dictionary.com and such can help with other synonyms.

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