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Embryos can be either "fresh" from fertilized egg cells of the same menstrual cycle, or "frozen", that is they have been generated in a preceding cycle and undergone embryo cryopreservation, and are thawed just prior to the transfer. The outcome from using cryopreserved embryos has uniformly been positive with no increase in birth defects or development abnormalities,[1] also between fresh versus frozen eggs used for intracytoplasmic sperm injection (ICSI).[2] Children born from vitrified blastocysts have significantly higher birthweight than those born from non-frozen blastocysts.[3] When transferring a frozen-thawed oocyte, the chance of pregnancy is essentially the same whether it is transferred in a natural cycle or one with ovulation induction.[4]

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