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A simple reflex involves a direct pathway that includes only a sensory neuron and a motor neuron, resulting in an immediate, involuntary response to a stimulus, such as the knee-jerk reflex. In contrast, a complex reflex involves multiple neurons and often includes interneurons, allowing for more intricate processing and integration of information, which can lead to a more coordinated response, such as withdrawal from pain. Simple reflexes are typically faster and more straightforward, while complex reflexes can involve higher brain functions and emotional responses.

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