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August Weismann disproved, or attempt to disprove the theory of Lamarckism (which states that: the adaptive trait gained by an organism during its life time can transfer to the new generation of organism; in contrast, proponents of this theory states: changes to genes can only be done through natural selection, and the experiences of changes to an organism's genes during its life time does not transfer), by cutting off the tails of mice, for many generations to observe changes to their traits. However, after many generations, no changes to the tail lengths of mice were observed. Thus, with this experiment and many that followed it, most considered Lamarckism to be disproved. However, during recent years, Lamarckism has garnered considerable interests, as observations have shown that Lamarckism does exist. For example, the epidemics of the population whose previous generation has experienced starvation is more likely to produce children, who, for generations, is likely to have genes with higher risk of high blood pressure.

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