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Floating within the cytosol are organelles, vesicles, and cytoskeletal structures, which are not considered part of the cytosol but are included in the cytoplasm. The cytosol is usually defined as the fluid portion of the cytoplasm, as defined by lysing the cell and separating out insoluble materials by centrifugation.

Cytosol is the jelly-like substance of the cytoplasm.

Cytoplasm being a colloid helps, because it makes the structure enough rigid yet enough smooth to help smooth functioning of the cell.

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