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If you do open one or more of them, you can contaminate them with microbes. These will most likely not be the ones you are trying to culture. It can give you a false negative.

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Q: Why is it important not to open sterile agar plates?
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Why is it important not to open sterile plates?

If you do open one or more of them, you can contaminate them with microbes. These will most likely not be the ones you are trying to culture. It can give you a false negative.


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