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Cons
*The body's tendency to reject foreign substances, including metallic or non-human tissue (e.g. animal tissue)
*Artificial hearts create more risks for clotting in the device
*Artificial hearts need to be replaced; they are not intended as a permanent fix
*Patients need to be on a heart lung machine and the longer they are on the machine the worse it is to their health.
*More likely than mechanical valves to structurally fail due to late calcification.
*Structural failure due to tears and perforations.
*Best in elderly patients ages 65 and greater due to less stress on prostheses and less risk of calcification.
*Better hemodynamic characteristics and less hemolysis.
Pros
*No anticoagulation therapy needed
*Only a small chance of rejection
*Improved hemodynamics
*No stent needed but stented valves are easier to implant
*Freedom from anticoagulation hemorrhage
*Low rate of serious thromboembolism
*Better hemodynamic characteristics and less hemolysis
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