Immunoglobulin A (IgA) is the primary antibody found in blood and respiratory secretions. It plays a crucial role in mucosal immunity, providing a first line of defense against pathogens in mucosal areas such as the respiratory tract. IgA exists in two forms: serum IgA, found in the bloodstream, and secretory IgA, which is present in mucosal secretions like saliva, tears, and respiratory fluids.
Normal values are IgA 70--400 mg/dl, but it may slightly differ in different laboratory
Abstract. These studies compared the ability of specific secretory IgA (sIgA) and IgG antibodies to promote phagocytosis of viable pseudomonas aeruginosa.
The secretory system does not really exist. There is a secretory mechanism that is part of the endocrine system, and that secretes hormones into the blood stream.
The immunoglobulin primarily found in colostrum is Immunoglobulin A (IgA). Colostrum, the first milk produced by mammals after giving birth, is rich in antibodies, particularly secretory IgA, which plays a crucial role in protecting the newborn's mucosal surfaces from infection. Additionally, colostrum contains other immunoglobulins like IgG and IgM, but IgA is the most abundant and significant for neonatal immunity.
High levels of immunoglobulin A (IgA) in the blood, known as hyper IgA, can indicate various conditions, including chronic infections, autoimmune diseases, or liver disorders. Elevated IgA may also be seen in certain genetic conditions. However, it is important to interpret these results in the context of other clinical findings and tests, as high IgA alone does not diagnose a specific condition. Consulting a healthcare provider is essential for proper evaluation and management.
Immunoglobulin A (IgA) is an antibody playing a critical role in mucosal immunity. More IgA is produced in mucosal linings than all other types of antibody combined. In its secretory form, it is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum, intestinal juice, vaginal fluid and secretions from the prostate and respiratory epithelium. Because it is resistant to degradation by enzymes, secretory IgA can survive in harsh environments such as the digestive and respiratory tracts, to provide protection against microbes that multiply in body secretions.Because the respiratory tract and sinus cavities are mucosal entities, the infections manifest here.
IgA Nephropathy is a kidney disease. It is more like a disorder, where the IgA-protein that helps the body fight infections, settles in the kidneys. Ultimately this results in a buildup of this protein in the kidneys, and later causes the kidneys to leak blood or protein in the urine.
IgA constitutes approximately 15% of the immunoglobulins within the body. Although it is found to some degree in the blood, it is present primarily in the secretions of the respiratory and gastrointestinal tract, in saliva, colostrum.
Granulocyte is a white blood cell with secretory granules in its cytoplasm, e.g, an eosinophil or a basophil
Glandular tissue is specialized for secretion and typically has a softer, spongier texture compared to other organs. It is often rich in blood vessels, ducts, and secretory cells, which give it a more gland-like appearance and function.
No. gA nephropathy (nuh-FROP-uh-the) is a common kidney disease that occurs when an antibody called immunoglobulin A (IgA) lodges in your kidneys. This hampers your kidneys' ability to filter waste, excess water and electrolytes from your blood. Over time, IgA nephropathy - also called Berger's disease - can lead to blood and protein in your urine, high blood pressure, and swollen hands and feet. IgA nephropathy usually progresses slowly over many years, and although some people eventually achieve complete remission, others develop end-stage kidney failure. No cure exists for IgA nephropathy, but certain medications can slow its course. Keeping your blood pressure under control and reducing your cholesterol levels also may help keep IgA nephropathy in check.