No,
All are made in the liver except for Factor VIII (made by the vascular endothelium) and vonWillebrand's factor which is made in the endothelium (in the Weibel-Palade bodies), megakaryocytes (α-granules of platelets), and subendothelial connective tissue.
Most are made in the liver
Heart Attacks 3x=s+e
Protein factors required for clotting are synthesized by the liver. These proteins include fibrinogen, prothrombin, and factors V, VII, VIII, IX, X, XI, and XII. Their synthesis is regulated by various factors including vitamin K.
The spleen is primarily involved in filtering blood and managing immune responses rather than synthesizing clotting factors. However, it does play a role in the recycling of iron from hemoglobin and the removal of old or damaged red blood cells. The primary site for the synthesis of clotting factors is the liver, where most of the clotting factors, including fibrinogen and prothrombin, are produced. Thus, no significant clotting factor is synthesized in the spleen.
In order for certain clotting factors( factors 2,7,9,and 10) to be synthesized in the liver Vit K must be present. Synthesized with the aide of our normal flora in our intestines, vit K synthesis can be compromised with the introduction of antibiotics that are generally non-discriminative towards bacteria in your body, killing both "good" and "bad" bacteria. Thus without vit k synthesis, necessary clotting factors are not synthesized either and can lead to the inability of your blood to clot as it normally would.
pancreas
Prothrombin is synthesized in the liver, specifically in the hepatocytes. It is then released into the bloodstream where it plays a critical role in the blood clotting cascade.
clotting factors
Lipase is an enzyme that helps break down food during digestion. No, lipase is not produced in the liver. It is produced in the pancreas.
Liver is responsible for the production of the clotting factors. Liver is the main organ of metabolism.
Yes, whole blood contains clotting factors such as fibrinogen, prothrombin, and platelets that help initiate the blood clotting process.
Insulin is synthesized in significant quantities only in beta cells in the pancreas.