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Alpha 1-antitrypsin deficiency primarily affects the lungs and liver, leading to conditions such as emphysema and liver disease. While it is not directly linked to memory loss, the associated complications, such as chronic hypoxia from lung issues or hepatic encephalopathy from liver dysfunction, could potentially contribute to cognitive impairments. Therefore, while memory loss is not a direct symptom of the deficiency itself, secondary effects from related health issues may impact cognitive function.

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1w ago

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Did Michael Jackson have alpha 1 antitrypsin deficiency?

Although the wide majority of Alpha 1's are of Northern European decent, most of us are not of one pure race. If he is an Alpha then both of his parents would have to be carriers of the gene. A simple blood test can determine if he was an Alpha and I don't know if that was done. Alpha 1 deficiency can cause either chronic COPD or liver disease. No one knows if Michael Jackson had Alpha-1 Antitrypsin Deficiency. The only source for the claim is Ian Halperin, a writer who did a biography of Jackson. Halperin provided no evidence whatever for this claim, and Jackson's spokesman denied it as "a total fabrication." Alpha-1 is considered rare in African Americans. However, the Alpha-1 Foundation recently awarded a grant to study the high rate of lung disease in African Americans, and to test them for Alpha-1 Antitrypsin Deficiency.


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