Can a male get prostate cancer without testes?

Answer 1

HI,

From my research, it may still be possible to develop prostate cancer without the testicles. I would say that it depends upon when the testicles were removed.

Since prostate cancer is such a slow developing cancer, it would seem possible to have prostate cancer prior to testicle removal (Orchiectomy or bilateral orchiectomy). However, one of the cancer's fuels is testosterone and related hormones (androgens). WebMD states that "Hormone treatment for prostate cancer is used to stop the production of testosterone and all androgens either temporarily or permanently....treatments can be given in many ways. Injections or pills are one method. Drugs can stop the testicles from producing testosterone and protect cells from any other androgens that remain in the body. " This chemical castration has the same effect as an orchiectomy.

However, if the testicles were removed prior to the typical age at which prostate cancer develops, there may not be enough testosterone in the body to nourish the cancer. So much of prostate cancer's presence is dependent upon heredity, diet, and environmental factors.

Hope this helps.