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Not by itself. Hydrocortisone is an anti-inflammatory agent and will help with the itching. In conjunction with cold sore medication (acyclovir) will help reduce the length of the infection.

--Original Homeopathic Solutions:

No. A cold sore is a viral infection, and hydrocortisone is for fungal or yeast infections. if you have a cold sore, use a cream specifically for that, or many people have found relief using tea tree oil applied several times a day to the area. Tea Tree oil is a natural remedy found in health stores and drug stores.

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13y ago

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