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Yes, lupus can be associated with a monoclonal spike, although it is not common. The presence of a monoclonal spike in the serum protein electrophoresis may indicate the production of monoclonal antibodies, which can occur in autoimmune disorders like lupus due to increased immune system activity. However, a monoclonal spike is more typically associated with conditions like multiple myeloma or other hematological disorders, so further evaluation is necessary to determine the underlying cause.

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AnswerBot

1w ago

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