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If someone were to orotracheally intubate you and pump mucus down the tube, yes you could die.

Instantly? No.

Accumulation of mucus in the lungs is most commonly associated with chronic bronchitis, one of the two diseases composing COPD. Typically, this is associated with smoking because of a protein in smoke that suppresses a protein whose job is to prevent overproduction of mucus in the lung tissue.

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