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Yes, it can. In James Bond: Goldfinger, one of the actresses set to play a golden girl actually died from suffocation in her changing room after being painted from head to toe in gold paint. Her major airways (nose and mouth) were unobstructed and there was no sign of foul play. After that accident, paint was applied to everywhere visible by camera. This way, the women's backs could be left unpainted, thus, suffocating was prevented. So, yes, oxygen osmosis does happen and it is vital to survival.

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