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Brain freeze is a headache most commonly associated with the quick consumption of cold substances, such as ice cream. When the cold substance comes into contact with your palate or the roof of your mouth and sinus cavities it causes the blood vessels to vasoconstrict or get smaller.

As the palate warms the blood vessels dilate. This rapid constriction and dilation is detected by pain receptors that travel to the brain via the trigaminal nerve, which also serves as one of the major nerves for the facial area. Because the pain signal travels with the signals coming from the face, the brain thinks it is feeling pain in the face that isn't really there, this is called referred pain.

The only way the brain is effected is how it perceives the information received from the nerve.

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