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Excessive free radicals within our bodies cause a condition known as "oxidative stress." Oxidative stress and energy depletion are characteristic biochemical hallmarks of Alzheimer's disease (AD), thus antioxidants with positive effects on glucose metabolism such as thioctic (alpha-lipoic) acid should exert positive effects in Alzheimer's patients. Initial studies (see the ralapure link below) show that treatment with alpha-lipoic acid might be a successful 'neuroprotective' therapy option for Alzheimer's Disease and related dementias.

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