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Pericarditis involves inflammation of the pericardium, the fibrous sac surrounding the heart. This inflammation can lead to the accumulation of fluid (pericardial effusion), thickening of the pericardial layers, and the potential formation of adhesions. The inflammatory process is often characterized by the infiltration of immune cells, such as lymphocytes and macrophages, which can result from infections, autoimmune diseases, or post-myocardial infarction. Symptoms typically include chest pain, which may worsen with deep breaths or coughing, and may be accompanied by fever and other signs of systemic inflammation.

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3w ago

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