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While most patients with Wolff-Parkinson-White syndrome can take antihistamines, I always recommend individual consultation before starting any medication. The concern with WPW is that some medications might potentially influence cardiac conduction pathways.

First-generation antihistamines (like diphenhydramine/Benadryl) have mild anticholinergic effects that could theoretically impact heart rhythm, though this is rarely clinically significant in stable WPW patients. Second-generation antihistamines (cetirizine, loratadine) are generally considered safer options with minimal cardiac effects.

Your specific case matters greatly - whether you've had ablation therapy, have symptomatic WPW, or take other medications could all influence this decision. Some antihistamines may interact with antiarrhythmic medications you might be taking.

If you need antihistamines, please schedule an appointment so we can review your complete medical history and current status. We can then select the most appropriate option for your situation.

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Hospital419ru

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4mo ago

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