If gangliosides were removed from the surface of target cells, cholera toxin would be unable to bind effectively to these cells. This would prevent the internalization of the toxin and its subsequent activation of adenylate cyclase, leading to a decrease in cAMP levels. Consequently, the disruption of ion transport and fluid secretion that characterizes cholera would be significantly diminished, likely reducing the severity of the disease. Overall, the absence of gangliosides would inhibit the pathogenic effects of cholera toxin.
on the outer surface of the target cell
Watermelon can be contaminated by cholera bacteria on their surface. But then the watermelons are carried to market and by that time the bacteria get killed after drying of watermelons. But then the watermelons can be contaminated like other foods and cause you cholera.
After synthesis in the ribosome, the polypeptide chain is usually transported to the endoplasmic reticulum (ER) where it undergoes post-translational modifications and folding. From the ER, the polypeptide enters the Golgi apparatus for further processing before being packaged into vesicles and transported to the cell surface. Finally, the vesicle fuses with the cell membrane, releasing the polypeptide to the cell surface.
When the surface of the heart is removed.
The surface on the machined part where the material is being removed.
If it doesn't give you any trouble it doesn't have to be removed.
Contaminated water directly causes Typhoid and Cholera but indirectly cause water breeding surface for mosquitoes which causes Malaria and Dengue
ores near earth's surface are removed by underground mining as long as they don't cause the mine to collapse as they drill.
They tore of the surface of the surfaces of the bacteria with the help of a blender.
surface tension
In the 19th century, cactus thorns were removed by sterilized sewing needles if they needed to be picked out. Or they were removed by poultices if they needed to be soaked up to the surface. Once at the surface, they were hand pulled out if they were big and visible enough. They were removed by sterilized sewing needles if they didn't come out on their own or by human hands. Or they were cut off at the surface if one end stuck out and the other was embedded. The embedded end then was left to be dissolved by the normal course of body biochemistry.
Gorilla glue can be removed from a surface by using acetone or nail polish remover. Apply the acetone to the glue, let it sit for a few minutes, then gently scrape or wipe it off with a cloth or sponge. Repeat as needed until the glue is completely removed.