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Cystic fibrosis is an example of an autosomal recessive genetic disease. It is caused by the mutation in the cystic fibrosis trans membrane regulator (CFTR) gene. This gene codes for a chloride ion channel important in creating digestive juices, mucus and sweat. A single mutated copy of the CFTR gene does not lead to disease. There have to be mutations in both alleles in order for the disease to manifest. Therefore, it is labeled as an autosomal recessive genetic disorder.

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16y ago

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