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"In about 10% of cases, ALS is caused by a genetic defect. In other cases, the cause is unknown.

In ALS, nerve cells (neurons) waste away or die, and can no longer send messages to muscles. This eventually leads to muscle weakening, twitching, and an inability to move the arms, legs, and body. The condition slowly gets worse. When the muscles in the chest area stop working, it becomes hard or impossible to breathe on one's own.Except for having a family member who has a hereditary form of the disease, there are no known risk factors."

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Scientists do not really know what causes ALS, although researchers do have a few ideas:

  • In 90-95 percent of people, there is no known cause and scientists call the disease "sporadic ALS."
  • In 5-10 percent of people, the disease is passed down through the families; scientists call it "familial ALS." A child who is born to somebody with familial ALS has a 50-percent chance of getting the disease.
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14y ago

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