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How is the intramembranous bone differ from that of the endochondral bone?
Intramembranous ossification [flat bones] & endochondral ossification [long bones].The essential between them is the presence or absence of cartilaginous phase.Intramembranous ossification occurs when mesenchymal precursor cells proliferate & subsequently differentiate directly into osteoblasts w/c mineralize an immature bone tissue called woven bone,characterize by irregular bundles of randomly oriented collagen fibers & an abundance of partially calcified immature new bone called asteoid.At later stages this woven bone is progressively remodeled to mature,lamellar bone. Endochondral ossification entails the conversion of a cartilaginous template into bone.Mesenchymal cells condense & differentiate into chondrocytes w/c secrete the cartilaginous matrix.This embryonic cartilage is avascular,& during its early development,a ring of woven bone is formed by intramembranous ossification in the future mid shaft area.This calcified woven bone is then invaded by vascular tissue,& osteoclasts & osteoblasts are recruited to replace the cartilage scaffold w/ bone matrix & excavate the hematopoietic bone marrow cavity.
When do primary centers of ossification first appear?
Primary centers of ossification first appear in the diaphysis of long bones during embryonic development, around the 8th week of gestation. This is where bone tissue begins to replace cartilage through endochondral ossification.
How does the bone replace the cartilage in the body?
Bone does not usually replace cartilage in the body. Instead, cartilage can be converted into bone during a process called endochondral ossification, which is essential for bone growth and development. This process involves the gradual replacement of cartilage with bone tissue.
What are the main events of endochondral ossification?
Meschyme (embryonic connective tissue) develops into a body of hyaline cartilage, covered with fibrous perichondrium, in the location of a future bone. For time, the perichondrium produces chondrocytes and the cartilage model growth in thickness.
What is the process of cartilage turning into hard adults bones?
Ossification
What marginal zone of the epiphyseal plate where in children and adolescents bone can be seen replacing the hyaline cartilage?
The region you are referring to is called the ossification or metaphysis zone of the epiphyseal plate. In this area, new bone tissue is formed as osteoblasts replace the hyaline cartilage. This process helps in the longitudinal growth of bones during childhood and adolescence.
What is it called when tissues are replace by harder minerals?
Ossification - tissue turns to bone Fossilisation - tissue turns to stone
When growth stops osteoclasts and osteoblasts cease their functioning?
No. You replace all of your bone tissue about every 8-9 years. It is constantly being remodeled.
The minerals found in bones are deposited by living cells called?
The minerals found in bones are deposited by living cells called osteoblasts. These cells are responsible for producing new bone tissue and laying down mineral deposits, such as calcium and phosphorus, to help strengthen and support the structure of bones.
What are bone forming cells?
Bone forming cells are a type of specialized cells called osteoblasts which are responsible for producing new bone tissue. Osteoblasts play a crucial role in bone formation by synthesizing and secreting the proteins and minerals needed to build and repair bone.
What is calcium buildup in muscle called?
Calcification in soft tissue, such as muscle, is called 'Calcinosis'. If it progresses into ossification (which involves the orderly deposition of calcium), it is called 'myositis ossificans'. However, the condition can occur in other connective tissue as well and may result from any kind of injury, including but not limited to inflammation. The term 'heterotropic ossification' has been proposed to replace it.
Do osteoclasts and osteoblasts cease their functioning when growth stops?
No, osteoclasts and osteoblasts continue to function throughout life to maintain bone health. While the rate of bone turnover may decrease after growth stops, these cells are still active in repairing damaged bone and adapting to changing mechanical stresses. This balance is important for bone remodeling and maintaining bone density.
