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One cannot look at Alzheimers as a familial dominant disease because only 0.1% of Alzheimers cases are inherited. But if you were to look at it that way, its not possible to skip generations because autosomal dominance doesn't work that way.

For example if a grand parent has Alzheimers and the son or daughter does not suffer, then the grand sons and grand daughters cannot suffer from the disease their grand father suffered from, i.e., they do not inherit Alzheimers. But as 99% of Alzheimers are sporadic they still may suffer from Alzheimers which has nothing to do with their Grand Daddy.

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15y ago

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